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These results support the importance of central sensory processing for motor learning.This review investigated the association between BD patient's states and the functioning of WM components. Meta-analysis of neuropsychological functioning in euthymic bipolar disorder: an update and investigation of moderator variables. For this purpose, we carried out a systematic review fulfilling a search in the databases Medline, Scopus, Sci ELO, and Web of Science using specific terms in the abstracts of the articles that generated 212 outcomes in the restricted period from 2005 to 2016. The confirmation of central sensory processing dependent motor learning in humans is discussed in the context of our prior report of preserved motor learning when sensation is disrupted peripherally. Physiologic evidence from animal lesion models suggests that sensory cortex is necessary for learning new skills, including movement sequences.For example, lesions to primary somatosensory cortex (S1) in cats [] inhibit motor learning.The patent shall certify the priority, authorship and exclusive right of the holder to use the utility model.Patent for utility model is valid for five years and may be extended for 3 years.This requirement is called - the unity of invention.Services: Utility model - a constructive implementation of capital goods and consumer goods, as well as their component parts.Working memory (WM) deficits are often reported in patients with Bipolar Disorder (BD). doi: 10.1111/j.1399-5618.2007.00327.x Pub Med Abstract | Cross Ref Full Text | Google Scholar Mc Cormack, C., Green, M. E., Roberts, G., Frankland, A., Hadzi-Pavlovic, D., et al. Neuropsychological and social cognitive function in young people at genetic risk of bipolar disorder. However, it is not clear about the nature of these WM deficits (update or serial order processes) and their association with each BD states (euthymic, mania, and depressive). doi: 10.1111/j.1399-5618.2011.00935.x Pub Med Abstract | Cross Ref Full Text | Google Scholar Martinez-Aran, A., Vieta, E., Torrent, C., Sanchez-Moreno, J., Goikolea, J., Salamero, M., et al. Functional outcome in bipolar disorder: the role of clinical and cognitive factors.